????Enervation??????
??????,????
?????:????? ? ????????
????Toxemia?intoxication?????
??????????????????????????????
????Irritation??
???????????--------?????????????,??????????????
????Inflammation??
????????????,??????;?????????????,???????
????Ulceration??
??????,?????,??????????
????Induration(tum or formation)?????
??????????,?????????????????,??????,?????????,??????????????????
????Cancer??
???????,?????????,??????,??????????????
????Type of Cancer
- ??????????????:??????
- ??????,???:??????,?????
- ???????(???????):??,??????????,??????
??????Risk Factors for Cancer
??????????????????,??????????????????????????
1?????????
????????????,?????????????,????????????,??????,?????????????????,????????,??????????12~20??
2???
?????????????:Wilms?,???????,??????,????????????????
3.???? ------ ?????
- ?? ------ ?????????????????????????
- ????
- ??????????????
- ??:?????????
- ??:??????????
- ??
- ???????,?????:???
- ?????:??????? : ??
- ?????:???????????;??,??????????
4.???
??????,????????,???????????,????????????????,??:?????????,?????,??????????????????,?????????,????,??????????,????????????
5.??
- ??? ------ ????????????
- ???? ------ ???
- ???????? ----- ??
- ?? ----- ?????????????????
6.???????
- ??????? ------ ????????,????????????????(???????)???????
- Diethystibesterol(DES)????????:???????????????????
- ??????????????????????????
- ?????????????????
7.???
???????????,???????????
- ???????(HPV) ------ ????
- B?C????? ------ ??
- ?????(Retrovirus) ------ ???????????,?????????????????
- E-B??(Epstein-Barr Virus) ------ ?????Burkitt s???,?????????
- ???? ------ ??????????????
- ??? ------ ??????????????????
- ???? ------ ??????
8.????
??????? ------ ???
????
????,?????????????????????????????????????
???
- ????
?????????,??????????????,??????????,???????,X???????????????????(?????),???(????)?
- ??????
??????????????????DNA,??????????DNA??????????????????????????
??????
| ??? |
??? |
| 1.????????? |
| ? |
? |
| ? |
???? |
| ??? |
?? |
| ?? |
?? |
| ??? |
? |
| ?? |
? |
| ????? |
?? |
| ? |
???? |
| ??? |
? |
| ? |
? |
| ??? |
?? |
| ????(Vinyl chloride) |
? |
| 2.??????? |
| ?? |
????? |
| ? |
???????????????? |
| 3.?????? |
| ????------ ??Topoisomerase??? : ????? |
????? |
| Diethylstibestrol |
???? : ??????????????????????????? |
?????????? : ????????????????? |
| Oxymetholone |
?? |
| ???? |
?? |
???????
????????????????????? ------ ????(Malignant transformation)
??,????
???????,????,?????????????,????????,???????,?????????????????;?????,????????
???,????
???????,??(???????)???????????,??????????????,?????????????????????????????????????????????????????????:????(X-ray,?????????)??????????,??????????????????
??? ????
- ????????????????/????????
- ??:???? ------ ?????????
???? ------ ?????????
|
